Abdominal obesity, specifically visceral fat, may raise colorectal cancer risk. Colorectal cancer is the third most frequent cancer worldwide.
Inflammation: Metabolically active visceral fat in the abdomen produces inflammatory chemicals. Chronic inflammation may contribute to cancer growth and progression.
Insulin Resistance: Obesity often causes insulin resistance. Insulin resistance can raise insulin levels, which may increase cancer cell development.
Adipose tissue (fat) produces hormones and signaling molecules called adipokines. Leptin and adiponectin imbalances may cause cancer.
Gut Microbiota: Obesity, specifically abdominal obesity, can change gut microbiota. Colorectal cancer risk increases with gut microbiota changes.
Absence of physical activity: Sedentary lifestyles are linked to abdominal obesity, which increases colorectal cancer risk. Regular exercise protects against cancer.
Colorectal cancer risk may be reduced by regular exercise, a balanced diet rich in fruits and vegetables, and weight management.
As always, cancer-risk individuals should speak with healthcare specialists for individualized advice and screenings.